HitPredict

Interactor 1: CRCM (P23508)
Colorectal mutant cancer protein (Protein MCC)
Gene: MCC

Interactor 2: NHRF2 (Q15599)
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)
Gene: NHERF2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 19555689
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 829 Hs			1 337
+	Hs
		153872 CRCM_HUMAN (1-829): 5.58e-54: 203: 100.00		NHRF1_HUMAN (2-337): 3.61e-70: 224: 48.87
+	Hs
		1236743 USBP1_HUMAN (232-811): 1.2e-86: 292: 25.80		USH1C_HUMAN (142-310): 4.02e-13: 71.9: 14.54
+	Hs
		617692 CRCM_HUMAN (1-829): 5.58e-54: 203: 100.00		WHRN_HUMAN (3-250): 2.49e-40: 152: 22.22
+	Hs
		617529 CRCM_HUMAN (1-829): 5.58e-54: 203: 100.00		DLG1_HUMAN (87-235): 1.55e-13: 73.5: 17.31
+	Hs
		617545 CRCM_HUMAN (1-829): 5.58e-54: 203: 100.00		SCRIB_HUMAN (4-185): 3.63e-13: 72.7: 18.37
+	Hs
		617632 CRCM_HUMAN (1-829): 5.58e-54: 203: 100.00		SNX27_HUMAN (149-228): 1.89e-09: 60.8: 38.71