HitPredict

Interactor 1: TNFL4 (P23510)
Tumor necrosis factor ligand superfamily member 4 (Glycoprotein Gp34) (OX40 ligand) (OX40L) (TAX transcriptionally-activated glycoprotein 1) (CD antigen CD252)
Gene: TNFSF4

Interactor 2: TNR4 (P43489)
Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134)
Gene: TNFRSF4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

The method score is based on:

Property	Details
Experiments	16905106, 8076595
Identification Methods	x-ray crystallography, molecular sieving, affinity chromatography technology
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002639 - positive regulation of immunoglobulin production GO:0005886 - plasma membrane GO:0006954 - inflammatory response GO:0006955 - immune response GO:0009986 - cell surface and 2 others more... GO:0043433 - negative regulation of DNA-binding transcription factor activity GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	183
Hs

1	277

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024