Interactor 1: NFYA (P23511)
Nuclear transcription factor Y subunit alpha (CAAT box DNA-binding protein subunit A) (Nuclear transcription factor Y subunit A) (NF-YA)
Gene: NFYA

Interactor 2: NFYB (P25208)
Nuclear transcription factor Y subunit beta (CAAT box DNA-binding protein subunit B) (Nuclear transcription factor Y subunit B) (NF-YB)
Gene: NFYB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 26496610, 25416956, 32296183, 8051128, 17098936, 15831478, 12857729, 16959611, unassigned1304, 15243141
Identification Methods affinity chromatography technology, two hybrid, pull down, two hybrid prey pooling approach, two hybrid array, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, validated two hybrid, biochemical, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CBFB_NFYA~CBFD_NFYB_HMF
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
and 8 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 347
Hs

1 207
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Sc
+ Ce
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024