HitPredict

Interactor 1: H2B1O (P23527)
Histone H2B type 1-O (H2B-clustered histone 17) (Histone H2B.2) (Histone H2B.n) (H2B/n)
Gene: H2BC17

Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 480
+	Mm
		682111 H2B2B_MOUSE (1-126): 1.28e-55: 171: 98.41		AKT1_MOUSE (1-480): 0: 587: 98.33
+	Mm
		682113 H2B1C_MOUSE (1-126): 7.88e-55: 169: 98.41		AKT1_MOUSE (1-480): 0: 587: 98.33
+	Hs
		420806 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		AKT1_HUMAN (1-480): 0: 586: 100.00
+	Hs
		681878 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		AKT1_HUMAN (1-480): 0: 586: 100.00
+	Hs
		681686 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		AKT1_HUMAN (1-480): 0: 586: 100.00
+	Hs
		617927 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		AKT2_HUMAN (1-477): 0: 559: 81.21
+	Hs
		420807 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		AKT2_HUMAN (1-477): 0: 559: 81.21
+	Hs
		682181 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		AKT2_HUMAN (1-477): 0: 559: 81.21
+	Hs
		408525 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67
+	Hs
		408583 H2BFS_HUMAN (1-126): 8.79e-55: 169: 96.03		KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67
+	Hs
		408591 H2B1C_HUMAN (1-126): 7.88e-55: 169: 98.41		KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67
+	Hs
		408624 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67
+	Hs
		408666 H2B1M_HUMAN (1-126): 3.31e-55: 169: 95.24		KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67
+	Hs
		408565 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		KPCB_HUMAN (14-477): 1.15e-148: 441: 36.67
+	Hs
		568756 H2B1H_HUMAN (1-126): 3.39e-55: 169: 99.21		KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53
+	Hs
		610760 H2B1H_HUMAN (1-126): 3.39e-55: 169: 99.21		KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86
+	Hs
		610687 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86
+	Hs
		617936 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		KS6A3_HUMAN (36-455): 4.1e-103: 325: 23.01
+	Hs
		420815 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		KS6A3_HUMAN (36-455): 4.1e-103: 325: 23.01
+	Hs
		850663 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		KS6A3_HUMAN (36-455): 4.1e-103: 325: 23.01