HitPredict

Interactor 1: H2B1O (P23527)
Histone H2B type 1-O (H2B-clustered histone 17) (Histone H2B.2) (Histone H2B.n) (H2B/n)
Gene: H2BC17

Interactor 2: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 129
+	Hs
		1151403 U3KQK0_HUMAN (1-126): 3e-56: 174: 97.62		H2A2A_HUMAN (1-127): 3.37e-65: 195: 97.64
+	Hs
		391992 U3KQK0_HUMAN (1-126): 3e-56: 174: 97.62		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		617974 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		H2AJ_HUMAN (1-129): 1.81e-66: 198: 96.90
+	Hs
		470411 H2B2F_HUMAN (1-126): 1.28e-55: 171: 98.41		H2A1_HUMAN (1-127): 5.35e-65: 195: 96.06
+	Hs
		1307102 H2B1M_HUMAN (1-126): 3.31e-55: 169: 95.24		H2A1J_HUMAN (1-127): 9.26e-66: 196: 96.06
+	Hs
		391736 H2B2F_HUMAN (1-126): 1.28e-55: 171: 98.41		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		470271 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		H2A1_HUMAN (1-127): 5.35e-65: 195: 96.06
+	Hs
		617952 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		H2A2A_HUMAN (1-127): 3.37e-65: 195: 97.64
+	Hs
		391552 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		420794 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		H2A1_HUMAN (1-127): 5.35e-65: 195: 96.06
+	Hs
		420844 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		H2A2A_HUMAN (1-127): 3.37e-65: 195: 97.64
+	Hs
		594822 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		H2A1D_HUMAN (1-127): 6.03e-65: 194: 95.28
+	Hs
		391503 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		391831 H2B1H_HUMAN (1-126): 3.39e-55: 169: 99.21		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		391868 H2B1M_HUMAN (1-126): 3.31e-55: 169: 95.24		H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49
+	Hs
		420804 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		H2A1D_HUMAN (1-127): 6.03e-65: 194: 95.28
+	Hs
		555496 H2B2F_HUMAN (1-126): 1.28e-55: 171: 98.41		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		555295 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		420800 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12
+	Hs
		555619 H2B1M_HUMAN (1-126): 3.31e-55: 169: 95.24		H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12