HitPredict

Interactor 1: H2B1O (P23527)
Histone H2B type 1-O (H2B-clustered histone 17) (Histone H2B.2) (Histone H2B.n) (H2B/n)
Gene: H2BC17

Interactor 2: JADE2 (Q9NQC1)
E3 ubiquitin-protein ligase Jade-2 (EC 2.3.2.27) (Jade family PHD finger protein 2) (PHD finger protein 15)
Gene: JADE2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 790
+	Hs
		617953 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		JADE1_HUMAN (4-790): 0: 683: 47.56
+	Hs
		1087195 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		JADE1_HUMAN (4-790): 0: 683: 47.56
+	Hs
		617963 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		JADE3_HUMAN (4-780): 0: 601: 40.68
+	Hs
		1087304 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		JADE3_HUMAN (4-780): 0: 601: 40.68
+	Hs
		918569 H2B1C_HUMAN (1-126): 7.88e-55: 169: 98.41		JADE3_HUMAN (4-780): 0: 601: 40.68
+	Hs
		319121 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		BRD1_HUMAN (7-790): 0: 589: 21.42
+	Hs
		319162 H2B1C_HUMAN (1-126): 7.88e-55: 169: 98.41		BRD1_HUMAN (7-790): 0: 589: 21.42
+	Hs
		319214 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		BRD1_HUMAN (7-790): 0: 589: 21.42
+	Hs
		617986 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		BRPF3_HUMAN (2-788): 0: 566: 19.93
+	Hs
		1087475 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		BRPF3_HUMAN (2-788): 0: 566: 19.93
+	Hs
		617938 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		BRPF1_HUMAN (7-750): 0: 558: 20.05
+	Hs
		876685 H2B1C_HUMAN (1-126): 7.88e-55: 169: 98.41		BRPF1_HUMAN (7-750): 0: 558: 20.05
+	Hs
		876694 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		BRPF1_HUMAN (7-750): 0: 558: 20.05
+	Hs
		299044 H2B1C_HUMAN (1-126): 7.88e-55: 169: 98.41		PHF14_HUMAN (99-742): 2.18e-118: 381: 19.12
+	Hs
		299062 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		PHF14_HUMAN (99-742): 2.18e-118: 381: 19.12
+	Hs
		876585 H2BFS_HUMAN (1-126): 8.79e-55: 169: 96.03		AF17_HUMAN (195-446): 1.71e-63: 232: 29.37
+	Hs
		876570 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		AF10_HUMAN (181-364): 3.17e-62: 228: 38.07
+	Hs
		152598 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		KMT2D_HUMAN (248-605): 2.35e-61: 228: 14.72
+	Hs
		301133 H2B1C_HUMAN (1-126): 7.88e-55: 169: 98.41		KDM4B_HUMAN (70-412): 2e-58: 218: 21.11
+	Hs
		918533 H2B1C_HUMAN (1-126): 7.88e-55: 169: 98.41		KMT2C_HUMAN (270-373): 7.54e-10: 65.1: 24.04