HitPredict

Interactor 1: IF4B (P23588)
Eukaryotic translation initiation factor 4B (eIF-4B)
Gene: EIF4B

Interactor 2: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29228324
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 611 Hs			1 164
+	Hs
		516361 IF4B_HUMAN (1-611): 6.54e-98: 313: 100.00		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		618613 IF4B_HUMAN (1-611): 6.54e-98: 313: 100.00		SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79
+	At
		286426 C3H42_ARATH (98-419): 3.96e-41: 154: 16.36		RSZ22_ARATH (11-82): 8.16e-19: 80.8: 55.56
+	Hs
		474017 PAB4L_HUMAN (6-198): 1.72e-27: 116: 13.40		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		951962 CIRBP_HUMAN (98-257): 1.65e-29: 116: 24.85		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		516466 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		516478 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		266904 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54
+	Hs
		516425 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14
+	Hs
		474021 PAB4L_HUMAN (6-198): 1.72e-27: 116: 13.40		PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09
+	Hs
		516495 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09
+	Hs
		516339 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		516689 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		PABP3_HUMAN (1-91): 6.48e-19: 84.6: 23.71
+	Hs
		516493 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79
+	Hs
		516674 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		RBM4_HUMAN (11-88): 3.45e-18: 81.9: 28.21
+	Mm
		665745 PABP1_MOUSE (49-537): 6.94e-25: 111: 10.22		TIA1_MOUSE (5-107): 1.59e-18: 82.6: 21.70
+	Hs
		516471 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		TIAR_HUMAN (1-95): 5.6e-18: 81.1: 26.00
+	Hs
		474020 PAB4L_HUMAN (6-198): 1.72e-27: 116: 13.40		SRSF6_HUMAN (11-88): 3.86e-16: 75.8: 47.44
+	Sc
		376562 PABP_YEAST (7-185): 1.17e-23: 107: 16.58		PABP_YEAST (2-93): 6.85e-19: 84.2: 20.62