HitPredict

Interactor 1: IF4B (P23588)
Eukaryotic translation initiation factor 4B (eIF-4B)
Gene: EIF4B

Interactor 2: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29228324
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 611 Hs			1 355
+	Hs
		161963 IF4B_HUMAN (1-611): 6.54e-98: 313: 100.00		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		516361 IF4B_HUMAN (1-611): 6.54e-98: 313: 100.00		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		453151 IF4B_HUMAN (1-611): 6.54e-98: 313: 100.00		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		516511 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		161948 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		516663 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		516424 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02
+	Hs
		474021 PAB4L_HUMAN (6-198): 1.72e-27: 116: 13.40		PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52
+	Hs
		516495 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52
+	Hs
		516339 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Sc
		376562 PABP_YEAST (7-185): 1.17e-23: 107: 16.58		PABP_YEAST (61-266): 4.09e-40: 150: 20.48
+	Hs
		516358 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Zm
		8143 A0A1D6ELH4_MAIZE (94-497): 7.01e-41: 159: 10.76		A0A1D6ELH4_MAIZE (184-269): 1.79e-14: 76.3: 13.79
+	Hs
		453350 CIRBP_HUMAN (98-257): 1.65e-29: 116: 24.85		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		453107 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		201699 MSI2H_HUMAN (82-179): 1.19e-27: 115: 18.37		MSI1H_HUMAN (21-180): 2.38e-16: 81: 28.13
+	Hs
		1288208 MSI2H_HUMAN (82-179): 1.19e-27: 115: 18.37		MSI2H_HUMAN (21-198): 1.49e-15: 78.3: 26.82
+	Hs
		516689 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		PABP3_HUMAN (172-267): 5.97e-16: 80.9: 16.50
+	Mm
		665745 PABP1_MOUSE (49-537): 6.94e-25: 111: 10.22		TIA1_MOUSE (176-270): 8.88e-14: 73.6: 18.75
+	Hs
		516471 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		TIAR_HUMAN (174-269): 2.98e-13: 72.1: 16.50