HitPredict

Interactor 1: IF4B (P23588)
Eukaryotic translation initiation factor 4B (eIF-4B)
Gene: EIF4B

Interactor 2: EIF3A (Q14152)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)
Gene: EIF3A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	29228324, 8816444, 16763566
Identification Methods	affinity chromatography technology, far western blotting, anti tag coimmunoprecipitation, coimmunoprecipitation, filter binding
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003743 - translation initiation factor activity GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 611 Hs			1 1382
+	Mm
		612541 IF4B_MOUSE (1-598): 2.36e-91: 296: 94.82		EIF3A_MOUSE (1-1382): 5.09e-106: 369: 89.01
+	Sc
		376765 PABP_YEAST (7-185): 1.17e-23: 107: 16.58		EIF3A_YEAST (7-893): 4.61e-76: 275: 23.40
+	Hs
		832977 PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72		YLPM1_HUMAN (774-1359): 8.27e-43: 174: 21.91
+	Hs
		832968 RBM3_HUMAN (98-241): 2.31e-22: 95.7: 24.83		YLPM1_HUMAN (774-1359): 8.27e-43: 174: 21.91
+	Hs
		516673 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		CP250_HUMAN (74-918): 1.12e-17: 92: 10.23