HitPredict

Interactor 1: PP2A2 (P23595)
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit (EC 3.1.3.16)
Gene: PPH22

Interactor 2: RUVB1 (Q03940)
RuvB-like protein 1 (RUVBL1) (EC 3.6.4.12) (TIP49-homology protein 1) (TIP49a homolog)
Gene: RVB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	11805837, 26831523
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 377 Sc			1 463
+	Sc
		618796 PP2A1_YEAST (1-377): 0: 562: 88.06		RUVB1_YEAST (1-463): 0: 682: 100.00
+	Hs
		738135 PP1G_HUMAN (66-374): 0: 527: 43.55		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Mm
		888047 PP1A_MOUSE (65-364): 0: 525: 45.18		RUVB1_MOUSE (2-461): 0: 682: 67.83
+	Hs
		906206 PP1A_HUMAN (65-364): 0: 524: 44.85		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Sc
		618870 PP2A2_YEAST (1-377): 0: 582: 100.00		RUVB2_YEAST (15-463): 0: 622: 41.15
+	Sc
		618807 PP2A1_YEAST (1-377): 0: 562: 88.06		RUVB2_YEAST (15-463): 0: 622: 41.15
+	Hs
		738134 PP1G_HUMAN (66-374): 0: 527: 43.55		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Hs
		906205 PP1A_HUMAN (65-364): 0: 524: 44.85		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Mm
		906384 PP1A_MOUSE (65-364): 0: 525: 45.18		RUVB2_MOUSE (1-458): 0: 636: 41.09
+	Sc
		594361 PP11_YEAST (79-377): 1.14e-130: 378: 54.75		RUVB1_YEAST (1-463): 0: 682: 100.00