HitPredict

Interactor 1: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Interactor 2: CCL6 (P27784)
C-C motif chemokine 6 (Protein C10) (Small-inducible cytokine A6) [Cleaved into: CCL6(22-95); CCL6(23-95)]
Gene: CCL6

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21731497
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0071346 - cellular response to type II interferon
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 424 Mm			1 116
+	Mm
		618899 IRF8_MOUSE (1-424): 0: 586: 100.00		CCL5_MOUSE (1-106): 3.9e-27: 97.5: 25.23
+	Hs
		1039468 IRF5_HUMAN (9-422): 1.01e-158: 458: 30.75		CCL19_HUMAN (36-113): 5.15e-21: 82.1: 23.46
+	Hs
		528263 IRF3_HUMAN (9-388): 6.95e-146: 423: 28.72		CCL5_HUMAN (34-106): 5.33e-23: 87.1: 29.73
+	Hs
		1056458 IRF3_HUMAN (9-388): 6.95e-146: 423: 28.72		CCL19_HUMAN (36-113): 5.15e-21: 82.1: 23.46
+	Hs
		962721 IRF9_HUMAN (5-385): 1.13e-130: 383: 34.01		CCL19_HUMAN (36-113): 5.15e-21: 82.1: 23.46
+	Hs
		528273 IRF7_HUMAN (12-383): 4.85e-111: 337: 21.46		CCL5_HUMAN (34-106): 5.33e-23: 87.1: 29.73
+	Hs
		1273342 IRF7_HUMAN (12-383): 4.85e-111: 337: 21.46		CCL19_HUMAN (36-113): 5.15e-21: 82.1: 23.46
+	Hs
		500980 IRF1_HUMAN (9-266): 9.31e-86: 266: 27.27		CCL5_HUMAN (34-106): 5.33e-23: 87.1: 29.73
+	Hs
		501084 IRF1_HUMAN (9-266): 9.31e-86: 266: 27.27		CCL19_HUMAN (36-113): 5.15e-21: 82.1: 23.46
+	Mm
		547383 IRF1_MOUSE (9-263): 5.48e-75: 238: 25.57		CCL5_MOUSE (1-106): 3.9e-27: 97.5: 25.23