Interactor 1: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Interactor 2: CASP1 (P29452)
Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
Gene: CASP1

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21731497
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0009617 - response to bacterium
GO:0042742 - defense response to bacterium
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 424
Mm

1 402
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024