HitPredict

Interactor 1: MP3B2 (A6NCE7)
Microtubule-associated proteins 1A/1B light chain 3 beta 2 (Microtubule-associated proteins 1A/1B light chain 3B-like)
Gene: MAP1LC3B2

Interactor 2: ATG3 (Q9NT62)
Ubiquitin-like-conjugating enzyme ATG3 (EC 2.3.2.-) (Autophagy-related protein 3) (APG3-like) (hApg3) (Protein PC3-96)
Gene: ATG3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	28514442, 33961781, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 125 Hs			1 314
+	Hs
		1326176 MLP3B_HUMAN (1-125): 7.02e-57: 174: 99.20		ATG3_HUMAN (1-314): 1.12e-158: 446: 100.00
+	Mm
		1265087 MLP3A_MOUSE (1-120): 8.49e-55: 168: 81.67		ATG3_MOUSE (1-314): 2.92e-158: 446: 97.45
+	Hs
		1330642 MLP3A_HUMAN (1-120): 8.49e-55: 168: 81.67		ATG3_HUMAN (1-314): 1.12e-158: 446: 100.00
+	Hs
		891336 GBRL2_HUMAN (7-120): 4.18e-53: 164: 38.60		ATG3_HUMAN (1-314): 1.12e-158: 446: 100.00
+	Hs
		306334 GBRAP_HUMAN (7-121): 1.17e-52: 163: 30.44		ATG3_HUMAN (1-314): 1.12e-158: 446: 100.00
+	Hs
		1315807 MLP3C_HUMAN (1-120): 3.23e-51: 160: 54.17		ATG3_HUMAN (1-314): 1.12e-158: 446: 100.00
+	Hs
		1328043 GBRL1_HUMAN (7-120): 2.69e-51: 159: 31.58		ATG3_HUMAN (1-314): 1.12e-158: 446: 100.00
+	At
		1013368 ATG8F_ARATH (3-120): 2.07e-58: 177: 36.44		ATG3_ARATH (17-314): 8.92e-122: 353: 46.41
+	Ce
		999358 LGG1_CAEEL (6-120): 1.01e-50: 158: 32.17		Q9N369_CAEEL (1-314): 2.55e-119: 347: 49.22
+	Ce
		1095400 LGG2_CAEEL (6-120): 8.89e-45: 143: 57.39		Q9N369_CAEEL (1-314): 2.55e-119: 347: 49.22
+	Pf
		83078 Q8IJK2_PLAF7 (6-120): 4.98e-45: 144: 30.65		C0H519_PLAF7 (3-314): 9.8e-111: 325: 37.11
+	Sc
		745998 ATG8_YEAST (4-120): 1.15e-54: 168: 33.33		ATG3_YEAST (8-311): 1.53e-97: 291: 33.13
+	Mm
		1246814 MLP3B_MOUSE (1-125): 8.36e-56: 171: 94.40		ATG10_MOUSE (173-301): 3.9e-44: 151: 20.59
+	Hs
		1326136 MLP3B_HUMAN (1-125): 7.02e-57: 174: 99.20		ATG10_HUMAN (173-301): 3.27e-41: 144: 20.59
+	Hs
		61902 MP3B2_HUMAN (1-125): 8.84e-57: 173: 100.00		ATG10_HUMAN (173-301): 3.27e-41: 144: 20.59
+	Hs
		891316 GBRL2_HUMAN (7-120): 4.18e-53: 164: 38.60		ATG10_HUMAN (173-301): 3.27e-41: 144: 20.59
+	Hs
		306312 GBRAP_HUMAN (7-121): 1.17e-52: 163: 30.44		ATG10_HUMAN (173-301): 3.27e-41: 144: 20.59
+	Hs
		1315801 MLP3C_HUMAN (1-120): 3.23e-51: 160: 54.17		ATG10_HUMAN (173-301): 3.27e-41: 144: 20.59
+	Hs
		1328025 GBRL1_HUMAN (7-120): 2.69e-51: 159: 31.58		ATG10_HUMAN (173-301): 3.27e-41: 144: 20.59