Interactor 1: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Interactor 2: TLR9 (Q9EQU3)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21731497
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006955 - immune response
GO:0032729 - positive regulation of type II interferon production
GO:0032735 - positive regulation of interleukin-12 production
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 424
Mm

1 1032
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024