HitPredict

Interactor 1: PP2A1 (P23635)
Minor serine/threonine-protein phosphatase PP2A-1 catalytic subunit (EC 3.1.3.16)
Gene: ppa1

Interactor 2: 2AAA (Q9UT08)
Protein phosphatase PP2A regulatory subunit A (Protein phosphatase 2A 65 kDa regulatory subunit) (PR65)
Gene: paa1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	22403715, 22119525, 24634168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HEAT~Metallophos, HEAT_2~Metallophos
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 Sp			1 590
+	Hs
		890979 PP4C_HUMAN (5-309): 0: 524: 62.75		PP4R4_HUMAN (13-589): 7.25e-66: 232: 15.32
+	Mm
		956531 PP4C_MOUSE (5-309): 0: 524: 62.75		PP4R4_MOUSE (13-589): 1.09e-64: 229: 15.84
+	Hs
		672399 PP2AB_HUMAN (9-309): 0: 532: 79.73		2AAB_HUMAN (90-590): 1.78e-45: 171: 19.21
+	Hs
		672402 PP2AA_HUMAN (9-309): 0: 532: 80.07		2AAB_HUMAN (90-590): 1.78e-45: 171: 19.21
+	Dm
		619857 PP2A_DROME (9-309): 0: 530: 78.41		2AAA_DROME (90-590): 8.79e-46: 172: 19.80
+	Hs
		672395 PP4C_HUMAN (5-309): 0: 524: 62.75		2AAB_HUMAN (90-590): 1.78e-45: 171: 19.21
+	Hs
		672072 PP2AB_HUMAN (9-309): 0: 532: 79.73		2AAA_HUMAN (193-590): 1.97e-31: 130: 19.40
+	Hs
		672079 PP2AA_HUMAN (9-309): 0: 532: 80.07		2AAA_HUMAN (193-590): 1.97e-31: 130: 19.40
+	Mm
		915332 PP2AB_MOUSE (9-309): 0: 532: 79.73		2AAA_MOUSE (193-590): 2.63e-31: 130: 19.40
+	Hs
		87319 PP2AB_HUMAN (9-309): 0: 532: 79.73		C9J9C1_HUMAN (220-590): 7.3e-31: 129: 20.80
+	Hs
		87320 PP2AA_HUMAN (9-309): 0: 532: 80.07		C9J9C1_HUMAN (220-590): 7.3e-31: 129: 20.80
+	Mm
		930638 PP2AA_MOUSE (9-309): 0: 531: 80.07		2AAA_MOUSE (193-590): 2.63e-31: 130: 19.40
+	Hs
		672060 PP4C_HUMAN (5-309): 0: 524: 62.75		2AAA_HUMAN (193-590): 1.97e-31: 130: 19.40
+	Sc
		618757 PP2A1_YEAST (4-309): 0: 524: 72.55		2AAA_YEAST (2-354): 4.28e-28: 121: 19.23
+	Sc
		618820 PP2A2_YEAST (4-309): 0: 522: 73.20		2AAA_YEAST (2-354): 4.28e-28: 121: 19.23
+	Hs
		268640 PP4C_HUMAN (5-309): 0: 524: 62.75		SF3B1_HUMAN (13-421): 5.46e-19: 93.4: 14.75
+	Hs
		915244 PP2AB_HUMAN (9-309): 0: 532: 79.73		PP4R1_HUMAN (25-265): 1.02e-10: 66.7: 15.81
+	Hs
		930933 PP2AA_HUMAN (9-309): 0: 532: 80.07		PP4R1_HUMAN (25-265): 1.02e-10: 66.7: 15.81
+	Bt
		61642 PP4C_BOVIN (5-309): 0: 524: 62.75		F1MRS1_BOVIN (296-556): 2.14e-12: 72.1: 18.82
+	Hs
		890987 PP4C_HUMAN (5-309): 0: 524: 62.75		PP4R1_HUMAN (25-265): 1.02e-10: 66.7: 15.81