HitPredict

Interactor 1: PSA2 (P23639)
Proteasome subunit alpha type-2 (Macropain subunit Y7) (Multicatalytic endopeptidase complex subunit Y7) (Proteasome component Y7) (Proteinase YSCE subunit 7)
Gene: PRE8

Interactor 2: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	32868373, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome, AAA~Proteasome_A_N, AAA_lid_3~Proteasome_A_N
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 250 Sc			1 437
+	Rn
		566253 PSA2_RAT (1-250): 5.07e-109: 315: 56.97		PRS8_RAT (43-437): 1.18e-135: 397: 41.29
+	At
		286455 PSA6B_ARATH (5-250): 1.23e-106: 309: 30.52		PRS4A_ARATH (19-428): 3e-135: 397: 37.74
+	Dm
		771287 PSA2_DROME (2-250): 2.44e-105: 306: 53.41		PRS4_DROME (27-428): 6.75e-136: 399: 37.99
+	Dm
		771327 PSA2_DROME (2-250): 2.44e-105: 306: 53.41		Q9W414_DROME (50-437): 3.69e-127: 375: 68.81
+	Dm
		771301 PSA2_DROME (2-250): 2.44e-105: 306: 53.41		Q8SZ19_DROME (50-437): 5.89e-127: 374: 68.56
+	At
		286460 PSA5A_ARATH (4-250): 7.87e-96: 282: 33.60		PRS4A_ARATH (19-428): 3e-135: 397: 37.74
+	At
		1114627 PSA5B_ARATH (4-250): 2.59e-95: 280: 33.20		PRS4A_ARATH (19-428): 3e-135: 397: 37.74
+	Dm
		820495 PSA5_DROME (3-250): 5e-93: 275: 30.59		PRS4_DROME (27-428): 6.75e-136: 399: 37.99
+	At
		286458 PSA4A_ARATH (1-230): 2.61e-92: 273: 32.91		PRS4A_ARATH (19-428): 3e-135: 397: 37.74
+	Dm
		1278655 PSA5_DROME (3-250): 5e-93: 275: 30.59		Q9W414_DROME (50-437): 3.69e-127: 375: 68.81
+	Dm
		771298 PSA2_DROME (2-250): 2.44e-105: 306: 53.41		Q7KMQ0_DROME (114-422): 1.29e-92: 288: 47.90
+	Sc
		619501 PSA2_YEAST (1-250): 4.68e-95: 280: 100.00		PRS8_YEAST (73-437): 2.68e-99: 304: 44.89
+	Sc
		619440 PSA2_YEAST (1-250): 4.68e-95: 280: 100.00		PRS7_YEAST (116-436): 9.22e-93: 289: 46.89
+	Dm
		1181022 PSA5_DROME (3-250): 5e-93: 275: 30.59		Q7KMQ0_DROME (114-422): 1.29e-92: 288: 47.90
+	Sc
		619413 PSA2_YEAST (1-250): 4.68e-95: 280: 100.00		CDC48_YEAST (3-414): 2.64e-82: 271: 28.04
+	Dm
		186105 PSA2_DROME (2-250): 2.44e-105: 306: 53.41		PRS8_DROME (1-147): 2.61e-09: 60.9: 9.32
+	Dm
		771310 PSA2_DROME (2-250): 2.44e-105: 306: 53.41		Q9V405_DROME (1-123): 2.61e-09: 60.9: 7.30
+	Dm
		1278638 PSA5_DROME (3-250): 5e-93: 275: 30.59		Q9V405_DROME (1-123): 2.61e-09: 60.9: 7.30
+	Dm
		186129 PSA5_DROME (3-250): 5e-93: 275: 30.59		PRS8_DROME (1-147): 2.61e-09: 60.9: 9.32
+	Hs
		656167 PSA5_HUMAN (3-250): 9.42e-92: 272: 30.04		PRS6B_HUMAN (1-123): 4.23e-09: 60.2: 8.03