HitPredict

Interactor 1: VPS3 (P23643)
Vacuolar protein sorting-associated protein 3 (Vacuolar protein-targeting protein 17)
Gene: VPS3

Interactor 2: PEP3 (P27801)
Vacuolar membrane protein PEP3 (Carboxypeptidase Y-deficient protein 3) (Vacuolar morphogenesis protein 8) (Vacuolar protein sorting-associated protein 18) (Vacuolar protein-targeting protein 18)
Gene: PEP3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

Property	Details
Experiments	23840658, 23417307, 17488625, 37968396, 34668759, 21325627, 20604902
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000329 - fungal-type vacuole membrane GO:0005768 - endosome GO:0031901 - early endosome membrane GO:0032889 - regulation of vacuole fusion, non-autophagic GO:0033263 - CORVET complex and 1 others more... GO:0099022 - vesicle tethering
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1011 Sc			1 918
+	Sc
		619694 VPS3_YEAST (1-1011): 0: 2023: 100.00		VPS41_YEAST (271-825): 8.52e-70: 252: 11.61
+	Sc
		522437 VPS3_YEAST (1-1011): 0: 2023: 100.00		PEP5_YEAST (315-856): 8.96e-67: 244: 12.62
+	Sc
		619706 VPS3_YEAST (1-1011): 0: 2023: 100.00		VAM6_YEAST (430-835): 6.98e-50: 193: 14.04
+	Sc
		619697 VPS3_YEAST (1-1011): 0: 2023: 100.00		VPS8_YEAST (496-863): 1.17e-10: 68: 11.06