Interactor 1: FUSED (P23647)
Serine/threonine-protein kinase fused (EC 2.7.11.1)
Gene: fu

Interactor 2: SMUF1 (Q9V853)
E3 ubiquitin-protein ligase Smurf1 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase Smurf1) (Lethal with a checkpoint kinase protein) (SMAD ubiquitination regulatory factor 1 homolog) (DSmurf)
Gene: Smurf

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 21145463
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007293 - germarium-derived egg chamber formation
GO:0030514 - negative regulation of BMP signaling pathway
GO:0045879 - negative regulation of smoothened signaling pathway
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 805
Dm

1 1061
+ Hs
+ Hs
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+ Hs
+ At
+ Hs
+ Xl
+ Hs
+ Sc
+ Hs

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Last updated: 15 Jul 2024