HitPredict

Interactor 1: GATA2 (P23769)
Endothelial transcription factor GATA-2 (GATA-binding protein 2)
Gene: GATA2

Interactor 2: GATA3 (P23771)
Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3)
Gene: GATA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35140242
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GATA~GATA
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001223 - transcription coactivator binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 14 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 480
Hs

1 443
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Sc
+ Ce
+ Sp
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024