HitPredict

Interactor 1: GATA2 (P23769)
Endothelial transcription factor GATA-2 (GATA-binding protein 2)
Gene: GATA2

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 2517
+	Hs
		620561 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		1272742 GATA6_HUMAN (108-429): 3.71e-66: 225: 38.44		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		1300980 TRPS1_HUMAN (153-447): 1.96e-56: 204: 23.76		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		620449 GATA2_HUMAN (1-480): 0: 529: 100.00		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		620385 GATA2_HUMAN (1-480): 0: 529: 100.00		KMT2C_HUMAN (1873-2516): 1.5e-09: 66.4: 10.57
+	Hs
		620486 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		SOX4_HUMAN (1091-1186): 2.77e-25: 114: 31.25
+	Hs
		620599 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		798797 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		818568 TRPS1_HUMAN (153-447): 1.96e-56: 204: 23.76		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		727938 TRPS1_HUMAN (153-447): 1.96e-56: 204: 23.76		SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28
+	Hs
		798895 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		MDC1_HUMAN (1380-2408): 4.76e-21: 104: 10.30
+	Hs
		727821 TRPS1_HUMAN (153-447): 1.96e-56: 204: 23.76		SOX5_HUMAN (833-1211): 2.27e-29: 129: 17.71
+	Hs
		818845 TRPS1_HUMAN (153-447): 1.96e-56: 204: 23.76		SOX9_HUMAN (1031-1201): 1.04e-24: 112: 23.08
+	Hs
		799053 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		554535 GATA1_HUMAN (186-480): 8.32e-69: 227: 43.35		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		799043 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Dm
		115546 Q9VF00_DROME (237-439): 4.1e-47: 175: 32.70		M9PFG6_DROME (1092-1190): 2.16e-26: 116: 32.32
+	Ce
		108367 ELT6_CAEEL (163-440): 1.22e-29: 120: 19.58		EGL13_CAEEL (1033-1238): 1.27e-41: 163: 20.00