HitPredict

Interactor 1: GATA2 (P23769)
Endothelial transcription factor GATA-2 (GATA-binding protein 2)
Gene: GATA2

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 2514
+	Hs
		620599 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		799053 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		554535 GATA1_HUMAN (186-480): 8.32e-69: 227: 43.35		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		261404 GATA2_HUMAN (1-480): 0: 529: 100.00		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261405 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		620439 GATA2_HUMAN (1-480): 0: 529: 100.00		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		620436 GATA2_HUMAN (1-480): 0: 529: 100.00		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Hs
		261432 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		620411 GATA2_HUMAN (1-480): 0: 529: 100.00		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		620385 GATA2_HUMAN (1-480): 0: 529: 100.00		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		620592 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		620586 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Hs
		620561 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		554529 GATA1_HUMAN (186-480): 8.32e-69: 227: 43.35		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Hs
		1355449 TRPS1_HUMAN (153-447): 1.96e-56: 204: 23.76		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		799043 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		1272742 GATA6_HUMAN (108-429): 3.71e-66: 225: 38.44		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		1300980 TRPS1_HUMAN (153-447): 1.96e-56: 204: 23.76		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33