HitPredict

Interactor 1: GATA3 (P23771)
Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3)
Gene: GATA3

Interactor 2: RCOR1 (Q9UKL0)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31409898, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0030218 - erythrocyte differentiation GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 443 Hs			1 485
+	Hs
		620586 GATA3_HUMAN (1-443): 2.52e-176: 502: 100.00		RCOR3_HUMAN (105-480): 6.86e-123: 369: 63.08
+	Hs
		620439 GATA2_HUMAN (1-443): 3.16e-135: 399: 61.24		RCOR1_HUMAN (1-485): 5.94e-148: 433: 100.00
+	Hs
		620565 GATA3_HUMAN (1-443): 2.52e-176: 502: 100.00		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		620436 GATA2_HUMAN (1-443): 3.16e-135: 399: 61.24		RCOR3_HUMAN (105-480): 6.86e-123: 369: 63.08
+	Hs
		1355449 TRPS1_HUMAN (139-433): 2.17e-73: 252: 24.10		RCOR1_HUMAN (1-485): 5.94e-148: 433: 100.00
+	Hs
		620517 GATA3_HUMAN (1-443): 2.52e-176: 502: 100.00		MDEAS_HUMAN (105-381): 6.79e-46: 173: 16.67
+	Hs
		554529 GATA1_HUMAN (186-443): 1.66e-60: 204: 40.56		RCOR3_HUMAN (105-480): 6.86e-123: 369: 63.08
+	Hs
		620368 GATA2_HUMAN (1-443): 3.16e-135: 399: 61.24		MDEAS_HUMAN (105-381): 6.79e-46: 173: 16.67
+	Hs
		261405 GATA3_HUMAN (1-443): 2.52e-176: 502: 100.00		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86
+	Hs
		620599 GATA3_HUMAN (1-443): 2.52e-176: 502: 100.00		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11
+	Hs
		1312040 TRPS1_HUMAN (139-433): 2.17e-73: 252: 24.10		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		798992 GATA4_HUMAN (134-436): 2.12e-72: 236: 38.87		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		1031969 TRPS1_HUMAN (139-433): 2.17e-73: 252: 24.10		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		798887 GATA4_HUMAN (134-436): 2.12e-72: 236: 38.87		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		296168 TRPS1_HUMAN (139-433): 2.17e-73: 252: 24.10		MTA2_HUMAN (85-446): 1.69e-64: 222: 16.67
+	Hs
		261404 GATA2_HUMAN (1-443): 3.16e-135: 399: 61.24		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86
+	Hs
		620449 GATA2_HUMAN (1-443): 3.16e-135: 399: 61.24		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11
+	Hs
		295956 GATA4_HUMAN (134-436): 2.12e-72: 236: 38.87		MTA2_HUMAN (85-446): 1.69e-64: 222: 16.67
+	Hs
		261432 GATA4_HUMAN (134-436): 2.12e-72: 236: 38.87		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86
+	Hs
		799053 GATA4_HUMAN (134-436): 2.12e-72: 236: 38.87		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11