HitPredict

Interactor 1: PCGF2 (P23798)
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (Melanoma nuclear protein 18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144)
Gene: PCGF2

Interactor 2: PHC1 (Q64028)
Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28)
Gene: PHC1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.562

Property	Details
Experiments	22325148, 12183370
Identification Methods	anti tag coimmunoprecipitation, two hybrid
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001739 - sex chromatin GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006338 - chromatin remodeling and 2 others more... GO:0016604 - nuclear body GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Mm			1 1010
+	Hs
		718390 PCGF2_HUMAN (1-342): 4.23e-95: 288: 95.91		PHC1_HUMAN (1-1010): 7.84e-87: 303: 91.98
+	Mm
		639473 BMI1_MOUSE (1-341): 1.86e-78: 244: 61.11		PHC1_MOUSE (1-1010): 6.25e-90: 311: 100.00
+	Hs
		717684 BMI1_HUMAN (1-341): 8.37e-81: 250: 61.40		PHC1_HUMAN (1-1010): 7.84e-87: 303: 91.98
+	Hs
		718418 PCGF2_HUMAN (1-342): 4.23e-95: 288: 95.91		SCMH1_HUMAN (603-1009): 3.03e-33: 139: 16.20
+	Hs
		718440 PCGF2_HUMAN (1-342): 4.23e-95: 288: 95.91		SCML1_HUMAN (870-1009): 8.93e-28: 117: 25.66
+	Hs
		554277 BMI1_HUMAN (1-341): 8.37e-81: 250: 61.40		MUC1_HUMAN (218-965): 1.84e-35: 148: 10.57
+	Hs
		718098 BMI1_HUMAN (1-341): 8.37e-81: 250: 61.40		SCMH1_HUMAN (603-1009): 3.03e-33: 139: 16.20
+	Hs
		718330 BMI1_HUMAN (1-341): 8.37e-81: 250: 61.40		SCML2_HUMAN (606-1009): 6.75e-30: 129: 15.27
+	Hs
		718311 BMI1_HUMAN (1-341): 8.37e-81: 250: 61.40		SCML1_HUMAN (870-1009): 8.93e-28: 117: 25.66
+	Mm
		620794 PCGF2_MOUSE (1-342): 5.75e-89: 272: 100.00		PHC2_MOUSE (9-592): 7.64e-15: 81.6: 18.48
+	Hs
		718412 PCGF2_HUMAN (1-342): 4.23e-95: 288: 95.91		PHC3_HUMAN (186-916): 7.04e-10: 65.4: 8.35
+	Hs
		718408 PCGF2_HUMAN (1-342): 4.23e-95: 288: 95.91		PHC2_HUMAN (38-597): 3.2e-09: 63.1: 11.05
+	Mm
		620790 PCGF2_MOUSE (1-342): 5.75e-89: 272: 100.00		PHC3_MOUSE (122-888): 6.87e-09: 61.9: 12.34
+	Mm
		639480 BMI1_MOUSE (1-341): 1.86e-78: 244: 61.11		PHC2_MOUSE (9-592): 7.64e-15: 81.6: 18.48
+	Hs
		1220909 R4GMX3_HUMAN (1-341): 3.13e-80: 254: 61.40		PHC2_HUMAN (38-597): 3.2e-09: 63.1: 11.05
+	Hs
		718028 BMI1_HUMAN (1-341): 8.37e-81: 250: 61.40		PHC3_HUMAN (186-916): 7.04e-10: 65.4: 8.35
+	Hs
		717999 BMI1_HUMAN (1-341): 8.37e-81: 250: 61.40		PHC2_HUMAN (38-597): 3.2e-09: 63.1: 11.05
+	Mm
		639476 BMI1_MOUSE (1-341): 1.86e-78: 244: 61.11		PHC3_MOUSE (122-888): 6.87e-09: 61.9: 12.34
+	Dr
		1225025 BMI1A_DANRE (1-341): 7.61e-75: 235: 60.70		PHC2_DANRE (1-562): 7.57e-09: 61.9: 20.71
+	Dr
		1186373 BMI1B_DANRE (1-340): 7.67e-72: 227: 57.06		PHC2_DANRE (1-562): 7.57e-09: 61.9: 20.71