HitPredict

Interactor 1: PCGF2 (P23798)
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (Melanoma nuclear protein 18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144)
Gene: PCGF2

Interactor 2: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.953

The method score is based on:

Property Details
Experiments 17296600, 20471950, 22325148, 12183370, 15741318, 16359901
Identification Methods affinity chromatography technology, two hybrid, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RAWUL~RAWUL, zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001739 - sex chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006325 - chromatin organization
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 342
Mm

1 336
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024