HitPredict

Interactor 1: MDM2 (P23804)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Interactor 2: RL5 (P47962)
Large ribosomal subunit protein uL18 (60S ribosomal protein L5)
Gene: Rpl5

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.666

Property	Details
Experiments	36435197, 17936560, 20832751, 22789538
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008097 - 5S rRNA binding
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 489 Mm			1 297
+	Hs
		805961 MDM2_HUMAN (1-488): 0: 636: 80.85		RL5_HUMAN (1-297): 4.71e-155: 436: 98.32