Interactor 1: MDM2 (P23804)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2
Interactor 2: ARF (Q64364)
Tumor suppressor ARF (Alternative reading frame) (ARF) (Cyclin-dependent kinase inhibitor 2A) (p19ARF)
Gene: Cdkn2a
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.55 | 0.718 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20832751, 10713175, 22378045, 15485902, 23580573, 9653180, 9529248, 11715018 |
| Identification Methods | affinity chromatography technology, pull down, coimmunoprecipitation, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0009410 - response to xenobiotic stimulus GO:0010468 - regulation of gene expression GO:0070301 - cellular response to hydrogen peroxide |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
