Interactor 1: MDM2 (P23804)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Interactor 2: RL11 (Q9CXW4)
Large ribosomal subunit protein uL5 (60S ribosomal protein L11)
Gene: Rpl11

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 20832751, 36435197, 15989966, 17936560, 22789538
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ribosomal_L5~zf-RanBP, Ribosomal_L5_C~zf-RanBP
Common GO terms GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008097 - 5S rRNA binding
GO:0010628 - positive regulation of gene expression
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 489
Mm

1 178
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024