HitPredict

Interactor 1: HXD12 (P23812)
Homeobox protein Hox-D12 (Homeobox protein Hox-4.7) (Homeobox protein Hox-5.6)
Gene: Hoxd12

Interactor 2: MEIS1 (Q60954)
Homeobox protein Meis1 (Myeloid ecotropic viral integration site 1)
Gene: MEIS1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.53	1.00	0.730

Property	Details
Experiments	20211142, 15617687
Identification Methods	two hybrid array, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Homeobox_KN~Homeodomain
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005667 - transcription regulator complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 268 Mm			1 390
+	Hs
		129958 HXC11_HUMAN (17-262): 2.97e-39: 140: 26.89		MEIS1_HUMAN (1-390): 7.65e-139: 402: 99.74
+	Mm
		678762 HXA2_MOUSE (47-265): 8.41e-36: 133: 22.83		MEIS1_MOUSE (1-390): 7.9e-139: 402: 100.00
+	Mm
		453088 HXB8_MOUSE (91-264): 6.39e-33: 122: 24.75		MEIS1_MOUSE (1-390): 7.9e-139: 402: 100.00
+	Mm
		488048 HXB4_MOUSE (196-260): 4.72e-32: 120: 47.69		MEIS1_MOUSE (1-390): 7.9e-139: 402: 100.00
+	Dm
		221160 UBX_DROME (52-261): 2.82e-33: 126: 22.79		HTH_DROME (1-389): 3.2e-87: 274: 47.00
+	Mm
		453090 HXB8_MOUSE (91-264): 6.39e-33: 122: 24.75		PKNX2_MOUSE (1-376): 1.74e-80: 256: 35.47
+	Mm
		192615 HXC12_MOUSE (1-268): 8.63e-37: 133: 38.28		PBX3_MOUSE (6-390): 1.25e-51: 180: 15.71
+	Hs
		678970 HXC8_HUMAN (101-263): 3.25e-37: 133: 28.99		PBX4_HUMAN (43-363): 2.15e-52: 180: 16.81
+	Mm
		192607 HXC6_MOUSE (69-259): 8.28e-34: 124: 22.77		PBX3_MOUSE (6-390): 1.25e-51: 180: 15.71
+	Mm
		192605 HXB8_MOUSE (91-264): 6.39e-33: 122: 24.75		PBX3_MOUSE (6-390): 1.25e-51: 180: 15.71
+	Hs
		447287 HXB5_HUMAN (111-260): 7.26e-33: 122: 25.00		PBX4_HUMAN (43-363): 2.15e-52: 180: 16.81
+	Hs
		567798 HXB8_HUMAN (91-264): 3.38e-33: 122: 24.75		PBX3_HUMAN (6-390): 8.78e-52: 180: 15.71
+	Mm
		192602 HXB5_MOUSE (107-260): 1.9e-32: 121: 22.08		PBX3_MOUSE (6-390): 1.25e-51: 180: 15.71
+	Dm
		950007 UBX_DROME (52-261): 2.82e-33: 126: 22.79		Q7JR08_DROME (203-388): 8.44e-41: 151: 25.13
+	Dm
		447330 SCR_DROME (155-260): 1.02e-33: 128: 30.17		EXD_DROME (223-388): 2.81e-39: 146: 24.85
+	Dm
		773222 UBX_DROME (52-261): 2.82e-33: 126: 22.79		EXD_DROME (223-388): 2.81e-39: 146: 24.85
+	Dm
		367183 ANTP_DROME (136-263): 4.28e-33: 125: 27.74		EXD_DROME (223-388): 2.81e-39: 146: 24.85
+	Mm
		193674 HXC12_MOUSE (1-268): 8.63e-37: 133: 38.28		PBX2_MOUSE (273-372): 7.66e-29: 118: 34.19
+	Hs
		678887 HXC8_HUMAN (101-263): 3.25e-37: 133: 28.99		PBX2_HUMAN (273-372): 1.59e-28: 117: 34.19
+	Hs
		447227 HXB5_HUMAN (111-260): 7.26e-33: 122: 25.00		PBX2_HUMAN (273-372): 1.59e-28: 117: 34.19