HitPredict

Interactor 1: GRIA1 (P23818)
Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)
Gene: GRIA1

Interactor 2: GRIA3 (Q9Z2W9)
Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3)
Gene: GRIA3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 12700243, 36417873
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan~SBP_bac_3, Lig_chan-Glu_bd~Lig_chan-Glu_bd, Lig_chan-Glu_bd~SBP_bac_3, SBP_bac_3~SBP_bac_3
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001919 - regulation of receptor recycling
GO:0004970 - glutamate-gated receptor activity
GO:0004971 - AMPA glutamate receptor activity
GO:0005886 - plasma membrane
and 18 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 907
Mm

1 888
+ Rn
+ Hs
+ Mm
+ Rn
+ Mm
+ Hs
+ Rn
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024