HitPredict

Interactor 1: GRIA2 (P23819)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 36417873
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan~SBP_bac_3, Lig_chan-Glu_bd~Lig_chan-Glu_bd, Lig_chan-Glu_bd~SBP_bac_3, SBP_bac_3~SBP_bac_3
Common GO terms GO:0001540 - amyloid-beta binding
GO:0004970 - glutamate-gated receptor activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
and 27 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 883
Mm

1 938
+ Hs
+ Hs
+ Rn
+ Mm
+ Rn
+ Mm
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Mm
+ Mm
+ Rn
+ Rn
+ Hs
+ Mm
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024