HitPredict

Interactor 1: GRIA2 (P23819)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: SRC8 (Q60598)
Src substrate cortactin
Gene: Cttn

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29515177, 19022416
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005886 - plasma membrane GO:0043197 - dendritic spine GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 883 Mm			1 546
+	Hs
		786734 GRIA2_HUMAN (1-883): 0: 928: 99.66		SRC8_HUMAN (1-546): 6.05e-164: 478: 92.18
+	Hs
		786733 GRIA2_HUMAN (1-883): 0: 928: 99.66		SPTN1_HUMAN (141-545): 1.96e-38: 153: 15.16
+	Mm
		723580 NMDZ1_MOUSE (1-868): 0: 575: 22.29		SRC8_MOUSE (1-546): 6.56e-168: 488: 100.00
+	Mm
		963725 NMDE2_MOUSE (28-845): 0: 570: 22.37		SRC8_MOUSE (1-546): 6.56e-168: 488: 100.00
+	Rn
		555251 GRIA4_RAT (1-860): 0: 852: 73.44		SPTN1_RAT (141-545): 3.46e-38: 152: 14.03
+	Hs
		984260 NMDZ1_HUMAN (1-868): 0: 572: 22.19		SPTN1_HUMAN (141-545): 1.96e-38: 153: 15.16