HitPredict

Interactor 1: GRIA2 (P23819)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: LNX2 (Q91XL2)
Ligand of Numb protein X 2 (Numb-binding protein 2)
Gene: LNX2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27889896
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030165 - PDZ domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 883 Mm			1 687
+	Hs
		786726 GRIA2_HUMAN (1-883): 0: 928: 99.66		DLG4_HUMAN (419-687): 8.9e-37: 149: 20.51
+	Mm
		620965 GRIA2_MOUSE (1-883): 0: 927: 100.00		DLG4_MOUSE (419-687): 9.75e-37: 149: 20.51
+	Hs
		786757 GRIA3_HUMAN (2-883): 0: 878: 71.46		DLG4_HUMAN (419-687): 8.9e-37: 149: 20.51
+	Mm
		1143566 GRIA3_MOUSE (2-883): 0: 876: 70.67		DLG4_MOUSE (419-687): 9.75e-37: 149: 20.51
+	Rn
		585151 GRIA1_RAT (4-862): 0: 862: 69.98		DLG1_RAT (279-686): 1.43e-40: 161: 19.09
+	Rn
		585138 GRIA1_RAT (4-862): 0: 862: 69.98		DLG4_RAT (419-687): 7.83e-37: 149: 20.51
+	Hs
		786696 GRIA1_HUMAN (4-862): 0: 866: 70.32		DLG1_HUMAN (272-687): 1.98e-35: 145: 15.17
+	Mm
		620892 GRIA1_MOUSE (4-862): 0: 859: 69.05		DLG4_MOUSE (419-687): 9.75e-37: 149: 20.51
+	Mm
		1143565 GRIA4_MOUSE (1-860): 0: 850: 72.29		DLG4_MOUSE (419-687): 9.75e-37: 149: 20.51
+	Mm
		620881 GRIA1_MOUSE (4-862): 0: 859: 69.05		DLG3_MOUSE (544-673): 2.79e-18: 91.6: 21.21
+	Mm
		620904 GRIA1_MOUSE (4-862): 0: 859: 69.05		DLG2_MOUSE (133-512): 7.54e-17: 87: 11.92
+	Hs
		942335 GRIK2_HUMAN (2-849): 0: 780: 38.67		DLG4_HUMAN (419-687): 8.9e-37: 149: 20.51
+	Rn
		677766 GRIK2_RAT (3-849): 0: 778: 38.59		DLG4_RAT (419-687): 7.83e-37: 149: 20.51
+	Mm
		761217 GRIK2_MOUSE (3-849): 0: 778: 38.59		DLG4_MOUSE (419-687): 9.75e-37: 149: 20.51
+	Hs
		1021483 GRIK2_HUMAN (2-849): 0: 780: 38.67		DLG1_HUMAN (272-687): 1.98e-35: 145: 15.17
+	Hs
		761199 GRIK1_HUMAN (11-880): 0: 761: 36.77		DLG4_HUMAN (419-687): 8.9e-37: 149: 20.51
+	Hs
		1022366 GRIK2_HUMAN (2-849): 0: 780: 38.67		DLG3_HUMAN (537-673): 7.06e-17: 87: 21.62
+	Hs
		942350 GRIK5_HUMAN (4-864): 0: 663: 33.98		DLG4_HUMAN (419-687): 8.9e-37: 149: 20.51
+	Mm
		1142982 GRIK5_MOUSE (4-864): 0: 661: 33.86		DLG4_MOUSE (419-687): 9.75e-37: 149: 20.51
+	Hs
		1081918 GRIK5_HUMAN (4-864): 0: 663: 33.98		DLG3_HUMAN (537-673): 7.06e-17: 87: 21.62