HitPredict

Interactor 1: IRF2 (P23906)
Interferon regulatory factor 2 (IRF-2)
Gene: IRF2

Interactor 2: TLR3 (Q99MB1)
Toll-like receptor 3 (CD antigen CD283)
Gene: TLR3

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12672806
Identification Methods	electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0034138 - toll-like receptor 3 signaling pathway GO:0051607 - defense response to virus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 349 Mm			1 905
+	Mm
		621184 IRF2_MOUSE (1-349): 0: 525: 100.00		TLR9_MOUSE (1-904): 6.16e-93: 318: 21.50
+	Mm
		547405 IRF1_MOUSE (1-288): 1.19e-109: 324: 42.91		TLR3_MOUSE (1-905): 2.49e-141: 444: 100.00
+	Mm
		547407 IRF1_MOUSE (1-288): 1.19e-109: 324: 42.91		TLR9_MOUSE (1-904): 6.16e-93: 318: 21.50
+	Hs
		179927 IRF2_HUMAN (1-349): 0: 510: 92.55		TLR3_HUMAN (5-429): 2.48e-24: 111: 18.26
+	Mm
		1145136 IRF4_MOUSE (7-146): 1.89e-66: 217: 41.43		TLR4_MOUSE (6-905): 1.07e-95: 321: 20.02
+	Mm
		619087 IRF8_MOUSE (7-125): 2.16e-59: 198: 47.06		TLR4_MOUSE (6-905): 1.07e-95: 321: 20.02
+	Mm
		619075 IRF8_MOUSE (7-125): 2.16e-59: 198: 47.06		TLR9_MOUSE (1-904): 6.16e-93: 318: 21.50
+	Hs
		179923 IRF1_HUMAN (1-265): 3.03e-103: 308: 44.73		TLR3_HUMAN (5-429): 2.48e-24: 111: 18.26
+	Mm
		618977 IRF8_MOUSE (7-125): 2.16e-59: 198: 47.06		TLR13_MOUSE (1-441): 2.93e-35: 146: 19.24
+	Hs
		237495 IRF3_HUMAN (1-146): 4.8e-52: 179: 31.97		TLR2_HUMAN (3-616): 2.17e-39: 159: 17.43
+	Hs
		179932 IRF8_HUMAN (7-139): 5.72e-59: 197: 41.48		TLR3_HUMAN (5-429): 2.48e-24: 111: 18.26
+	Hs
		120153 IRF4_HUMAN (7-145): 2.95e-63: 209: 41.01		TLR4_HUMAN (32-397): 1.34e-12: 73.7: 15.28
+	Hs
		120146 IRF8_HUMAN (7-139): 5.72e-59: 197: 41.48		TLR4_HUMAN (32-397): 1.34e-12: 73.7: 15.28