HitPredict

Interactor 1: IRF2 (P23906)
Interferon regulatory factor 2 (IRF-2)
Gene: IRF2

Interactor 2: TLR9 (Q9EQU3)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16301648
Identification Methods	electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051607 - defense response to virus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 349 Mm			1 1032
+	Mm
		547407 IRF1_MOUSE (1-288): 1.19e-109: 324: 42.91		TLR9_MOUSE (1-1032): 1.73e-175: 541: 100.00
+	Mm
		619075 IRF8_MOUSE (7-125): 2.16e-59: 198: 47.06		TLR9_MOUSE (1-1032): 1.73e-175: 541: 100.00
+	Hs
		179927 IRF2_HUMAN (1-349): 0: 510: 92.55		TLR3_HUMAN (18-600): 1.56e-37: 154: 17.39
+	Mm
		621183 IRF2_MOUSE (1-349): 0: 525: 100.00		TLR3_MOUSE (9-270): 3.89e-12: 72.6: 16.48
+	Mm
		618977 IRF8_MOUSE (7-125): 2.16e-59: 198: 47.06		TLR13_MOUSE (4-1024): 9.32e-93: 319: 22.76
+	Hs
		179923 IRF1_HUMAN (1-265): 3.03e-103: 308: 44.73		TLR3_HUMAN (18-600): 1.56e-37: 154: 17.39
+	Mm
		547405 IRF1_MOUSE (1-288): 1.19e-109: 324: 42.91		TLR3_MOUSE (9-270): 3.89e-12: 72.6: 16.48
+	Hs
		179932 IRF8_HUMAN (7-139): 5.72e-59: 197: 41.48		TLR3_HUMAN (18-600): 1.56e-37: 154: 17.39
+	Mm
		1145136 IRF4_MOUSE (7-146): 1.89e-66: 217: 41.43		TLR4_MOUSE (37-621): 4.34e-28: 124: 17.34
+	Mm
		619087 IRF8_MOUSE (7-125): 2.16e-59: 198: 47.06		TLR4_MOUSE (37-621): 4.34e-28: 124: 17.34
+	Hs
		120153 IRF4_HUMAN (7-145): 2.95e-63: 209: 41.01		TLR4_HUMAN (5-483): 2.44e-17: 89.5: 17.80
+	Hs
		120146 IRF8_HUMAN (7-139): 5.72e-59: 197: 41.48		TLR4_HUMAN (5-483): 2.44e-17: 89.5: 17.80
+	Hs
		237495 IRF3_HUMAN (1-146): 4.8e-52: 179: 31.97		TLR2_HUMAN (36-534): 3.51e-21: 101: 18.22