HitPredict

Interactor 1: CRYAB (P23927)
Alpha-crystallin B chain (Alpha(B)-crystallin) (P23)
Gene: CRYAB

Interactor 2: CE290 (Q6A078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein homolog) (Nephrocystin-6)
Gene: Cep290

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21565611
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0043010 - camera-type eye development
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 175 Mm			1 2472
+	Hs
		528430 HSPB8_HUMAN (1-155): 1.22e-42: 142: 32.16		MYH8_HUMAN (1482-2471): 5.17e-35: 149: 12.25
+	Hs
		1356177 HSPB8_HUMAN (1-155): 1.22e-42: 142: 32.16		MYH2_HUMAN (1558-2471): 7.64e-33: 142: 10.00
+	Hs
		522580 HSPB8_HUMAN (1-155): 1.22e-42: 142: 32.16		MYH1_HUMAN (1558-2471): 2.33e-31: 137: 10.44
+	Hs
		1356186 HSPB8_HUMAN (1-155): 1.22e-42: 142: 32.16		MYH4_HUMAN (1558-2471): 2.21e-30: 134: 10.11
+	Hs
		502931 HSPB8_HUMAN (1-155): 1.22e-42: 142: 32.16		MYH3_HUMAN (1677-2471): 3.49e-27: 123: 11.95
+	Hs
		61510 HSPB2_HUMAN (15-149): 3.29e-38: 130: 42.22		A5YM51_HUMAN (1895-2471): 1.98e-20: 102: 13.17
+	Hs
		148272 HSPB1_HUMAN (7-174): 2.52e-52: 167: 41.08		CTRO_HUMAN (1922-2404): 3.76e-09: 64.9: 16.23
+	Hs
		528397 HSPB8_HUMAN (1-155): 1.22e-42: 142: 32.16		MYH6_HUMAN (133-1263): 2.09e-14: 82: 13.16
+	Hs
		528375 HSPB2_HUMAN (15-149): 3.29e-38: 130: 42.22		MYH6_HUMAN (133-1263): 2.09e-14: 82: 13.16
+	Dm
		404257 Q9VSA9_DROME (31-172): 2.96e-34: 119: 27.47		MYSA_DROME (1935-2465): 9e-10: 66.6: 11.21
+	Dm
		113819 M9NHC5_DROME (46-163): 4.39e-32: 114: 34.75		MYSA_DROME (1935-2465): 9e-10: 66.6: 11.21