Interactor 1: ITAL (P24063)
Integrin alpha-L (CD11 antigen-like family member A) (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (Lymphocyte antigen 15) (Ly-15) (CD antigen CD11a)
Gene: Itgal

Interactor 2: ZAP70 (P43404)
Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)
Gene: ZAP70

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 24584089
Identification Methods affinity chromatography technology
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001772 - immunological synapse
GO:0005911 - cell-cell junction
GO:0019722 - calcium-mediated signaling
GO:0050850 - positive regulation of calcium-mediated signaling
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1162
Mm

1 618
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024