HitPredict

Interactor 1: CDKA1 (P24100)
Cyclin-dependent kinase A-1 (CDKA;1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog A) (CDC2aAt)
Gene: CDKA-1

Interactor 2: CDKE1 (Q84TI6)
Cyclin-dependent kinase E-1 (CDKE;1) (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin-dependent kinase 8) (Protein HUA ENHANCER 3)
Gene: CDKE-1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 17426018, 20407024
Identification Methods affinity chromatography technology, protein complementation assay, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0008353 - RNA polymerase II CTD heptapeptide repeat kinase activity
GO:0016310 - phosphorylation
and 1 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 294
At

1 470
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Mm
+ At

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Last updated: 15 Jul 2024