HitPredict

Interactor 1: CDKA1 (P24100)
Cyclin-dependent kinase A-1 (CDKA;1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog A) (CDC2aAt)
Gene: CDKA-1

Interactor 2: CCU11 (Q9LJ45)
Cyclin-U1-1 (CycU1;1) (Cyclin-P2.1) (CycP2;1)
Gene: CYCU1-1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.80	0.741

Property	Details
Experiments	24951878, 15197472
Identification Methods	two hybrid, fluorescent resonance energy transfer, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Cyclin~Pkinase
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 294 At			1 210
+	At
		621726 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCU21_ARATH (18-202): 1.44e-64: 200: 40.31
+	At
		621696 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCU43_ARATH (17-205): 3.77e-64: 199: 37.57
+	At
		621714 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCU42_ARATH (12-191): 6.04e-64: 198: 36.67
+	At
		621719 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCU22_ARATH (20-202): 2.31e-63: 198: 38.86
+	At
		1227956 CKB21_ARATH (1-291): 3.62e-129: 371: 53.51		CCU11_ARATH (1-210): 2.13e-78: 235: 100.00
+	At
		285423 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCU41_ARATH (17-204): 8.37e-62: 193: 40.43
+	At
		621675 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCU31_ARATH (51-179): 5.19e-50: 163: 51.16
+	Sc
		565447 PHO85_YEAST (3-292): 2.27e-129: 371: 51.51		PHO80_YEAST (7-208): 3.28e-59: 189: 25.85
+	At
		639348 CKB11_ARATH (1-292): 4.04e-129: 371: 54.07		CCU31_ARATH (51-179): 5.19e-50: 163: 51.16
+	Sc
		565624 PHO85_YEAST (3-292): 2.27e-129: 371: 51.51		PCL7_YEAST (7-178): 1.09e-48: 162: 29.32
+	Sc
		565812 PHO85_YEAST (3-292): 2.27e-129: 371: 51.51		PCL8_YEAST (12-190): 8.13e-39: 140: 15.96
+	Sc
		565612 PHO85_YEAST (3-292): 2.27e-129: 371: 51.51		PCL6_YEAST (6-190): 4.39e-37: 135: 19.55
+	Sc
		339662 CDK1_YEAST (3-289): 4.61e-129: 370: 61.30		PCL6_YEAST (6-190): 4.39e-37: 135: 19.55
+	Sc
		565703 PHO85_YEAST (3-292): 2.27e-129: 371: 51.51		PCL10_YEAST (12-171): 2.72e-35: 130: 21.43
+	Hs
		960325 CDK5_HUMAN (1-293): 1.66e-131: 376: 55.78		CNPD1_HUMAN (43-181): 3.84e-32: 121: 24.31
+	Sc
		565463 PHO85_YEAST (3-292): 2.27e-129: 371: 51.51		PCL1_YEAST (24-169): 9.17e-35: 125: 20.13
+	Sp
		383461 CDK1_SCHPO (1-291): 1.46e-130: 374: 60.74		CGP1_SCHPO (66-172): 3.27e-26: 105: 21.82
+	Sc
		565844 PHO85_YEAST (3-292): 2.27e-129: 371: 51.51		PCL9_YEAST (60-169): 3.26e-27: 106: 23.01
+	Sc
		565475 PHO85_YEAST (3-292): 2.27e-129: 371: 51.51		PCL2_YEAST (65-169): 7.58e-26: 103: 25.93
+	Sc
		565583 PHO85_YEAST (3-292): 2.27e-129: 371: 51.51		PCL5_YEAST (68-172): 1.5e-26: 103: 21.82