HitPredict

Interactor 1: PRTN3 (P24158)
Myeloblastin (EC 3.4.21.76) (AGP7) (C-ANCA antigen) (Leukocyte proteinase 3) (PR-3) (PR3) (Neutrophil proteinase 4) (NP-4) (P29) (Wegener autoantigen)
Gene: PRTN3

Interactor 2: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 256 Hs			1 448
+	Hs
		621816 PRTN3_HUMAN (1-256): 5.43e-109: 316: 100.00		TBA1C_HUMAN (1-448): 0: 726: 96.21
+	Hs
		621799 PRTN3_HUMAN (1-256): 5.43e-109: 316: 100.00		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		428023 PRTN3_HUMAN (1-256): 5.43e-109: 316: 100.00		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		1309494 TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10		TBA1C_HUMAN (1-448): 0: 726: 96.21
+	Hs
		714751 TRY3_HUMAN (15-251): 6.12e-98: 290: 33.87		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		933614 TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		933554 KLK6_HUMAN (9-250): 1.54e-91: 271: 30.16		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		1309527 KLK11_HUMAN (25-250): 6.76e-89: 266: 30.71		TBA1C_HUMAN (1-448): 0: 726: 96.21
+	Hs
		933221 PRSS8_HUMAN (18-256): 1.49e-92: 277: 26.52		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		1175177 TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		933653 KLK11_HUMAN (25-250): 6.76e-89: 266: 30.71		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		1175223 KLK11_HUMAN (25-250): 6.76e-89: 266: 30.71		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		428427 TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		933971 TMPS5_HUMAN (4-250): 7.93e-92: 279: 29.10		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		486167 GRAB_HUMAN (23-250): 1.88e-87: 261: 38.49		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		595527 GRAH_HUMAN (22-250): 3.27e-41: 143: 37.08		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		439340 CATG_HUMAN (22-248): 1.63e-41: 144: 37.55		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		595544 GRAH_HUMAN (22-250): 3.27e-41: 143: 37.08		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		427973 CATG_HUMAN (22-248): 1.63e-41: 144: 37.55		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		428017 GRAH_HUMAN (22-250): 3.27e-41: 143: 37.08		TBB5_HUMAN (1-439): 0: 697: 40.55