HitPredict

Interactor 1: PRTN3 (P24158)
Myeloblastin (EC 3.4.21.76) (AGP7) (C-ANCA antigen) (Leukocyte proteinase 3) (PR-3) (PR3) (Neutrophil proteinase 4) (NP-4) (P29) (Wegener autoantigen)
Gene: PRTN3

Interactor 2: FRAS1 (Q86XX4)
Extracellular matrix organizing protein FRAS1 (Fraser syndrome 1 protein)
Gene: FRAS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 256 Hs			1 4008
+	Hs
		1204963 KLK11_HUMAN (25-250): 6.76e-89: 266: 30.71		FRAS1_HUMAN (1-4008): 0: 2806: 100.00
+	Hs
		621376 CMA1_HUMAN (23-248): 3.92e-46: 155: 40.25		FRAS1_HUMAN (1-4008): 0: 2806: 100.00
+	Hs
		439344 CATG_HUMAN (22-248): 1.63e-41: 144: 37.55		FRAS1_HUMAN (1-4008): 0: 2806: 100.00
+	Hs
		621371 CMA1_HUMAN (23-248): 3.92e-46: 155: 40.25		FREM2_HUMAN (1296-3338): 2.12e-108: 393: 18.62
+	Hs
		439338 CATG_HUMAN (22-248): 1.63e-41: 144: 37.55		FREM2_HUMAN (1296-3338): 2.12e-108: 393: 18.62
+	Mm
		378815 GRAB_MOUSE (23-250): 7.19e-90: 267: 35.98		NOTC1_MOUSE (4-946): 8.71e-59: 229: 12.95
+	Hs
		428693 TRY1_HUMAN (8-251): 9.12e-103: 300: 33.20		AGRV1_HUMAN (1121-3205): 1.27e-35: 153: 12.28
+	Hs
		980428 TM11B_HUMAN (8-246): 2.66e-89: 272: 24.05		NOTC2_HUMAN (567-1139): 7.18e-39: 163: 13.53
+	Hs
		486154 GRAB_HUMAN (23-250): 1.88e-87: 261: 38.49		NOTC1_HUMAN (5-694): 7.39e-38: 160: 13.02
+	Hs
		664194 TMPS4_HUMAN (5-246): 3.48e-92: 280: 26.54		PCSK6_HUMAN (314-564): 3.29e-18: 94.9: 20.90
+	Hs
		589592 KLK2_HUMAN (10-251): 1.59e-89: 267: 30.83		PCSK6_HUMAN (314-564): 3.29e-18: 94.9: 20.90
+	Hs
		1055016 TMPS4_HUMAN (5-246): 3.48e-92: 280: 26.54		FAT1_HUMAN (208-422): 2.76e-12: 75.8: 10.19
+	Hs
		341357 PLMN_HUMAN (25-248): 3.15e-89: 282: 35.42		LAMA1_HUMAN (865-1036): 6.38e-09: 64.9: 18.09
+	Hs
		1055020 KLK11_HUMAN (25-250): 6.76e-89: 266: 30.71		FAT1_HUMAN (208-422): 2.76e-12: 75.8: 10.19
+	Hs
		380900 GRAB_HUMAN (23-250): 1.88e-87: 261: 38.49		VWF_HUMAN (748-1118): 4.47e-10: 68.7: 14.78
+	Hs
		621379 CMA1_HUMAN (23-248): 3.92e-46: 155: 40.25		AGRV1_HUMAN (1121-3205): 1.27e-35: 153: 12.28
+	Hs
		621366 CMA1_HUMAN (23-248): 3.92e-46: 155: 40.25		FAT1_HUMAN (208-422): 2.76e-12: 75.8: 10.19
+	Hs
		621384 CMA1_HUMAN (23-248): 3.92e-46: 155: 40.25		CELR2_HUMAN (985-1093): 1.37e-10: 70.4: 16.36
+	Hs
		621373 CMA1_HUMAN (23-248): 3.92e-46: 155: 40.25		FAT4_HUMAN (2-88): 4.91e-10: 68.5: 9.89
+	Hs
		621385 CMA1_HUMAN (23-248): 3.92e-46: 155: 40.25		CELR1_HUMAN (213-451): 3.32e-09: 65.8: 12.20