Interactor 1: CD3Z (P24161)
T-cell surface glycoprotein CD3 zeta chain (T-cell receptor T3 zeta chain) (CD antigen CD247)
Gene: Cd247

Interactor 2: ZAP70 (P43404)
Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)
Gene: ZAP70

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.633

The method score is based on:

Property Details
Experiments 10358158, 24584089, 24034254
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002250 - adaptive immune response
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0042101 - T cell receptor complex
GO:0050852 - T cell receptor signaling pathway
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 164
Mm

1 618
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024