HitPredict

Interactor 1: ZBT25 (P24278)
Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP)
Gene: ZBTB25

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 435 Hs			1 522
+	Hs
		622108 ZBT25_HUMAN (1-435): 4.06e-80: 255: 100.00		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		200285 ZBT43_HUMAN (2-403): 8.74e-68: 224: 17.41		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		1230265 BCL6B_HUMAN (2-419): 1.13e-74: 243: 15.08		TRAF4_HUMAN (54-500): 6.36e-91: 287: 26.11
+	Hs
		66771 A8KA13_HUMAN (2-419): 9.7e-74: 240: 14.82		TRAF4_HUMAN (54-500): 6.36e-91: 287: 26.11
+	Hs
		549155 ZN250_HUMAN (31-287): 3.69e-61: 209: 10.08		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		1020938 PATZ1_HUMAN (2-420): 9.43e-56: 197: 18.03		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		563532 ZNF23_HUMAN (57-427): 4.16e-89: 285: 11.98		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		1313364 ZBT26_HUMAN (3-382): 7.28e-53: 184: 15.18		TRAF4_HUMAN (54-500): 6.36e-91: 287: 26.11
+	Hs
		1020737 ZN544_HUMAN (49-237): 1.31e-39: 152: 7.94		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		1019333 ZBTB2_HUMAN (1-429): 7.46e-89: 281: 33.48		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59
+	Hs
		549156 ZN250_HUMAN (31-287): 3.69e-61: 209: 10.08		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		1023804 PATZ1_HUMAN (2-420): 9.43e-56: 197: 18.03		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		563305 ZNF16_HUMAN (107-427): 1.46e-83: 271: 11.68		RN151_HUMAN (54-204): 2.32e-33: 128: 28.03
+	Hs
		70987 ZBT42_HUMAN (1-396): 3.54e-63: 211: 15.68		TRI68_HUMAN (60-385): 1.41e-42: 160: 12.91
+	Hs
		536720 ZN250_HUMAN (31-287): 3.69e-61: 209: 10.08		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		1235566 ZBTB2_HUMAN (1-429): 7.46e-89: 281: 33.48		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84
+	Hs
		301834 ZNF74_HUMAN (32-319): 7.68e-38: 147: 10.35		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		536849 ZNF74_HUMAN (32-319): 7.68e-38: 147: 10.35		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		200298 ZBT43_HUMAN (2-403): 8.74e-68: 224: 17.41		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84
+	Hs
		1252492 ZBT26_HUMAN (3-382): 7.28e-53: 184: 15.18		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84