HitPredict

Interactor 1: MCM3 (P24279)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (Minichromosome maintenance protein 3)
Gene: MCM3

Interactor 2: CDT1 (P47112)
Cell division cycle protein CDT1 (SIC1 indispensable protein 2) (Topoisomerase-A hypersensitive protein 11)
Gene: TAH11

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.946

The method score is based on:

Property	Details
Experiments	16824194, 31385807, 22045335, 25087873, 22250202, 25085418
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	CDT1_C~MCM, CDT1_C~MCM_lid, CDT1_C~MCM_OB
Common GO terms	GO:0000727 - double-strand break repair via break-induced replication GO:0003688 - DNA replication origin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005656 - nuclear pre-replicative complex and 2 others more... GO:0005737 - cytoplasm GO:0006267 - pre-replicative complex assembly involved in nuclear cell cycle DNA replication
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	971
Sc

1	604

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024