Interactor 1: MCM3 (P24279)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (Minichromosome maintenance protein 3)
Gene: MCM3

Interactor 2: CDC45 (Q08032)
Cell division control protein 45
Gene: CDC45

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 9554851, 15755447, 26255844, 17018296, 28869037, 25313033, 25659432, 28510759, 28373564, 32804080, 37968396, 21362622, 25342810, 25870112, 32075754, 31728581, 32585006, 24692448, 21179020
Identification Methods coimmunoprecipitation, affinity chromatography technology, pull down, biochemical, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC45~MCM_lid, CDC45~MCM_N, CDC45~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003682 - chromatin binding
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
and 6 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 971
Sc

1 650
+ Hs
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+ Dm
+ Hs
+ Hs
+ Hs
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+ Dm
+ Dm
+ Dm
+ Dm
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+ Hs

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Last updated: 15 Jul 2024