Interactor 1: ALAT1 (P24298)
Alanine aminotransferase 1 (ALT1) (EC 2.6.1.2) (Glutamate pyruvate transaminase 1) (GPT 1) (Glutamic--alanine transaminase 1) (Glutamic--pyruvic transaminase 1)
Gene: GPT

Interactor 2: ALAT2 (Q8TD30)
Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2)
Gene: GPT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Aminotran_1_2~Aminotran_1_2
Common GO terms GO:0004021 - L-alanine:2-oxoglutarate aminotransferase activity
GO:0009058 - biosynthetic process
GO:0030170 - pyridoxal phosphate binding
GO:0042853 - L-alanine catabolic process
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 496
Hs

1 523
+ At
+ At
+ At
+ Dm
+ At
+ At
+ At
+ At
+ At
+ Ce
+ Hs
+ Hs
+ At
+ Ec
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024