HitPredict

Interactor 1: LET23 (P24348)
Receptor tyrosine-protein kinase let-23 (EC 2.7.10.1) (Lethal protein 23)
Gene: let-23

Interactor 2: LET23 (P24348)
Receptor tyrosine-protein kinase let-23 (EC 2.7.10.1) (Lethal protein 23)
Gene: let-23

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.755

The method score is based on:

Property Details
Experiments 29358026, 26060020
Identification Methods x-ray crystallography, pull down
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Furin-like~Furin-like, Furin-like~GF_recep_IV, Furin-like~Recep_L_domain, GF_recep_IV~GF_recep_IV, GF_recep_IV~Recep_L_domain, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, Recep_L_domain~Recep_L_domain
Common GO terms GO:0002119 - nematode larval development
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005006 - epidermal growth factor receptor activity
GO:0005524 - ATP binding
GO:0005911 - cell-cell junction
and 21 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Ce

1 1323
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Last updated: 15 Jul 2024