HitPredict

Interactor 1: LET23 (P24348)
Receptor tyrosine-protein kinase let-23 (EC 2.7.10.1) (Lethal protein 23)
Gene: let-23

Interactor 2: SNT1 (Q93646)
Syntrophin-1
Gene: stn-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	21110867
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1323 Ce			1 440
+	Hs
		665569 EPHB2_HUMAN (478-1322): 1.08e-180: 564: 17.39		AFAD_HUMAN (42-355): 8.97e-42: 160: 17.88
+	Hs
		665667 EPHB2_HUMAN (478-1322): 1.08e-180: 564: 17.39		LIN7C_HUMAN (37-142): 6.49e-42: 148: 36.79
+	Hs
		876391 EPHA7_HUMAN (510-1237): 5.01e-172: 540: 16.97		AFAD_HUMAN (42-355): 8.97e-42: 160: 17.88
+	Hs
		1072612 EPHA7_HUMAN (510-1237): 5.01e-172: 540: 16.97		LIN7C_HUMAN (37-142): 6.49e-42: 148: 36.79
+	Hs
		872718 EPHA4_HUMAN (510-1181): 3.08e-172: 540: 18.59		LIN7C_HUMAN (37-142): 6.49e-42: 148: 36.79
+	Hs
		665186 EPHA2_HUMAN (478-1190): 8.61e-167: 525: 18.92		AFAD_HUMAN (42-355): 8.97e-42: 160: 17.88
+	Hs
		872496 EPHA5_HUMAN (511-1181): 1.57e-164: 521: 18.61		LIN7C_HUMAN (37-142): 6.49e-42: 148: 36.79
+	Hs
		1021499 EPHA7_HUMAN (510-1237): 5.01e-172: 540: 16.97		DLG1_HUMAN (30-332): 3.36e-25: 110: 18.51
+	Hs
		872639 EPHA4_HUMAN (510-1181): 3.08e-172: 540: 18.59		DLG1_HUMAN (30-332): 3.36e-25: 110: 18.51
+	Hs
		665663 EPHB2_HUMAN (478-1322): 1.08e-180: 564: 17.39		GOPC_HUMAN (33-152): 2.69e-15: 79.7: 36.67
+	Hs
		872433 EPHA5_HUMAN (511-1181): 1.57e-164: 521: 18.61		DLG1_HUMAN (30-332): 3.36e-25: 110: 18.51
+	Hs
		665433 EPHA3_HUMAN (510-1181): 1.33e-176: 551: 19.97		GOPC_HUMAN (33-152): 2.69e-15: 79.7: 36.67
+	Hs
		872402 EPHB3_HUMAN (524-1147): 6.1e-145: 468: 19.91		AFAD_HUMAN (42-355): 8.97e-42: 160: 17.88
+	Hs
		1072604 EPHA7_HUMAN (510-1237): 5.01e-172: 540: 16.97		GOPC_HUMAN (33-152): 2.69e-15: 79.7: 36.67
+	Hs
		872713 EPHA4_HUMAN (510-1181): 3.08e-172: 540: 18.59		GOPC_HUMAN (33-152): 2.69e-15: 79.7: 36.67
+	Hs
		872493 EPHA5_HUMAN (511-1181): 1.57e-164: 521: 18.61		GOPC_HUMAN (33-152): 2.69e-15: 79.7: 36.67
+	Mm
		1142638 ERBB4_MOUSE (380-1304): 1.91e-138: 458: 21.64		DLG4_MOUSE (34-336): 5.88e-27: 115: 18.83
+	Hs
		383736 ERBB2_HUMAN (382-1323): 1.51e-139: 459: 21.61		DLG4_HUMAN (34-336): 1.26e-26: 114: 18.51
+	Hs
		942346 ERBB4_HUMAN (634-1304): 1.31e-114: 392: 23.92		DLG4_HUMAN (34-336): 1.26e-26: 114: 18.51
+	Hs
		1021496 ERBB4_HUMAN (634-1304): 1.31e-114: 392: 23.92		DLG1_HUMAN (30-332): 3.36e-25: 110: 18.51