HitPredict

Interactor 1: PRP22 (P24384)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22 (EC 3.6.4.13)
Gene: PRP22

Interactor 2: SN114 (P36048)
Pre-mRNA-splicing factor SNU114 (114 kDa U5 small nuclear ribonucleoprotein component) (Growth inhibitory protein 10)
Gene: SNU114

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	29146870, 20089683
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0071007 - U2-type catalytic step 2 spliceosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1145 Sc			1 1008
+	Sp
		193836 PRP22_SCHPO (1-1138): 0: 918: 44.27		SN114_SCHPO (1-1007): 0: 841: 32.82
+	Sc
		589425 PRP2_YEAST (252-1113): 0: 837: 34.18		SN114_YEAST (1-1008): 0: 895: 100.00
+	Hs
		1064544 PRP16_HUMAN (105-1139): 0: 809: 35.69		U5S1_HUMAN (2-1007): 0: 898: 31.43
+	Dm
		525379 Q9VR29_DROME (445-1106): 0: 825: 39.38		EF2_DROME (117-995): 0: 842: 24.65
+	Hs
		195443 DHX15_HUMAN (471-1112): 0: 746: 47.10		U5S1_HUMAN (2-1007): 0: 898: 31.43
+	Sc
		731745 PRP43_YEAST (416-1106): 0: 700: 45.80		SN114_YEAST (1-1008): 0: 895: 100.00
+	Hs
		1064722 DHX35_HUMAN (437-1114): 0: 691: 45.10		U5S1_HUMAN (2-1007): 0: 898: 31.43
+	Hs
		994175 DHX9_HUMAN (109-1144): 0: 683: 20.04		U5S1_HUMAN (2-1007): 0: 898: 31.43
+	Sc
		554215 PRP16_YEAST (217-1109): 0: 670: 35.31		SN114_YEAST (1-1008): 0: 895: 100.00
+	Sp
		194922 DHX15_SCHPO (410-1129): 0: 716: 44.82		SN114_SCHPO (1-1007): 0: 841: 32.82