HitPredict

Interactor 1: CCND1 (P24385)
G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)
Gene: CCND1

Interactor 2: TSC2 (P49815)
Tuberin (Tuberous sclerosis 2 protein)
Gene: TSC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	16357142, 26977878
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 295 Hs			1 1807
+	Hs
		538495 CCNB1_HUMAN (5-282): 3.94e-89: 273: 20.64		TSC2_HUMAN (1-1807): 0: 2708: 100.00
+	Hs
		590144 CCNA2_HUMAN (3-286): 6.9e-81: 252: 24.48		TSC2_HUMAN (1-1807): 0: 2708: 100.00
+	Hs
		673040 CCND2_HUMAN (3-295): 5.15e-81: 248: 61.22		TSC2_HUMAN (1-1807): 0: 2708: 100.00
+	Hs
		673131 CCND3_HUMAN (3-295): 2.73e-76: 236: 51.69		TSC2_HUMAN (1-1807): 0: 2708: 100.00
+	Dm
		114632 Q7KUZ5_DROME (10-269): 2.99e-72: 231: 36.77		M9PD17_DROME (1255-1756): 5.21e-86: 315: 31.22