HitPredict

Interactor 1: IL4RA (P24394)
Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124) [Cleaved into: Soluble interleukin-4 receptor subunit alpha (Soluble IL-4 receptor subunit alpha) (Soluble IL-4R-alpha) (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)]
Gene: IL4R

Interactor 2: STAT6 (P42226)
Signal transducer and activator of transcription 6 (IL-4 Stat)
Gene: STAT6

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.710

The method score is based on:

Property Details
Experiments 11313257, 9651359, 9392697, 21268015, 8816495
Identification Methods pull down, unspecified method, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0007165 - signal transduction
GO:0019221 - cytokine-mediated signaling pathway
GO:0035771 - interleukin-4-mediated signaling pathway
GO:0120162 - positive regulation of cold-induced thermogenesis
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 825
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024